Saturday, August 1, 2015

French Maritime Pine Bark: Pycnogenol


It is summer “cold” season. A fever in the winter is bearable but a fever in the summer heat it is hideous. My favorite herb for colds and flu is pine bark.

The active ingredient in French Maritime Pine Bark is pycnogenol. Pycnogenol is any group of flavinoids (chemical molecules) extracted from pine bark. Pycnogenol® has become the registered trademark of supplements made from French maritime pine trees.

A French explorer discovered the benefits of French maritime pine bark extract in the 1500′s. The largest maritime pine trees forest is located in southwestern France near the Bordeaux region. This forest plantation dates back to the times of Napoleon III. The maritime pine tree can be found throughout parts of Spain, Italy, Morocco and Portugal. In the 1950′s Jacques Masquelier began to seriously research beneficial properties of pine bark.

French maritime pine bark (pinus pinaster) comes from trees that grow in the Landes Forest of southwestern France. It should not be confused with White Pine Bark (pinus strobes). White pine is also known as: Eastern White Pine, Northern White Pine, Pumpkin Pine, Soft Pine, Deal Pine, Weymouth Pine, Pin du Lord, and Pinus Alba. The White Pine is an evergreen conifer native to eastern North America and has been cultivated throughout Europe. Medicinal White Pine Bark comes from the inner bark of the White Pine tree, or from young shoots and twigs. The bark is dried, and then used in powdered form, tea, syrups, as a poultice, and in capsules.

I have never used White Pine as an herbal medicine. I am however a true believer in French Maritime Pine Bark, Pycnogenol. It helped me with a terrible case of bronchitis and a sinus infection. 

The makers of Pycnogenol®, French maritime pine bark (pinus pinaster), follow good agricultural practice (GAP) and good manufacturing practice (GMP). This means there is absolutely no application of pesticides to pine trees or use of toxic solvents during the manufacture.

French maritime pine bark (pinus pinaster), Pycnogenol has been researched extensively. It is used for treating circulation problems, allergies, asthma, ringing in the ears, high blood pressure, muscle soreness, pain, osteoarthritis, diabetes, attention deficit-hyperactivity disorder (ADHD), a disease of the female reproductive system called endometriosis, menopausal symptoms, painful menstrual periods, erectile dysfunction (ED), and an eye disease called retinopathy.

Pycnogenol is used to slow the aging process, maintain healthy skin, improve athletic endurance, and improve male fertility. It is also used for preventing disorders of the heart and blood vessels, including stroke, heart disease, and varicose veins. Anti-aging” products contain pycnogenol.

Two capsules are taken 2 hours before the flight and then again 6 hours later. Also, taking pycnogenol 100 mg before a flight, 6 hours after the flight, and the following day appears to reduce the risk of blood clots forming in the veins during long flights, and once the next day reduces swelling and ankle swelling.

The Memorial Sloan Kettering Cancer Center website tells us Pycnogenol is derived from the bark of the French maritime pine tree. Studies have displayed effectiveness in treating many inflammatory conditions, skin disorders, and poor blood circulation. Pycnogenol has antioxidant and anti-inflammatory properties. It is effective in treating erectile dysfunction when used in combination with L-arginine. Recent animal studies show pycnogenol exhibits protective effects against cardiac toxicity caused by the chemotherapy drug doxorubicin, however human data is needed.

The Memorial Sloan Kettering website reports the primary constituents of pine bark extracts are procyanidins and phenolic acids. Pine bark extract acts as an antioxidant by increases the activities of antioxidant enzymes and by increasing the intracellular glutathione levels. It inhibits production the proteins that cause inflammation and atherosclerosis.

An in vitro (in the test tube) study suggests that Pycnogenol induces apoptosis in human breast cancer cells causing them to die. Other in vitro studies show it reduces neuronal apoptosis (neuron death), an important factor of Alzheimer’s disease.

There are no known interactions with foods.

Scientific research has studied the following dosages by mouth:
For allergies: 50 mg twice daily.
For asthma in children: 1 mg per pound of body weight given in two divided doses.
For poor circulation: 45-360 mg daily, or 50-100 mg three times daily.
For diseases of the retina, including those related to diabetes: 50 mg three times daily.
For mild high blood pressure: 200 mg of pycnogenol daily.
For improving exercise capacity in athletes: 200 mg daily.

Special precautions & warnings:

Sloan-Kettering Cancer Center tells us pycnogenol is effective for treating allergies, however for some people pyncogenol is actually an allergen. Some rare and possibly fatal allergies can develop. Signs of an allergic reaction to including wheezing or shortness of breath, rash, chest pain, and swelling of body parts including the face, hands or feet.

If pregnant or breast-feeding pycnogenol should be used cautiously or avoided as there is not enough available research. It may be safe for children when taken by mouth, short-term. If you have an autoimmune disease it’s best to avoid using pycnogenol. High doses of pycnogenol might increase the risk of bleeding in people with bleeding conditions. High doses of pycnogenol might decrease blood sugar too much in people who are taking diabetes medication. Stop using pycnogenol at least 2 weeks before a scheduled surgery as it might increase the chance of bleeding during and after surgery.
Because pycnogenol increases the immune system it might decrease the effectiveness of medications that decrease the immune system (Immunosuppressants).

Avoid taking pycnogenol with aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Avoid taking pycnogenol with herbs and supplements that can lower blood sugar such as alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others.

Avoid using pycnogenol with herbs that slow blood clotting such as angelica, clove, danshen, garlic, ginger, ginkgo, Panax ginseng, and others.


http://www.pycnogenol.com/




https://www.mskcc.org/cancer-care/integrative-medicine/herbs/pine-bark-extract


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